Persister Cells Evade Killing by Antimicrobial and Anticancer Compounds

Persister Cells Evade Killing by Antimicrobial and Anticancer Compounds

Webinar topics include:

  • Persistence, observed in many eukaryotic and prokaryotic cell types, is a transient cell sate that allows organisms to temporarily survive unusually high levels of drugs
  • Despite their non-proliferating state, persister cells have an active, but unique, metabolism that regulates their reversible switching and maintenance
  • Our results confirm that metabolism represents a rich source of targets for anti-persistence strategies
  • Incorporating the use of Phenotype MicroArrays™ for examining metabolic activity in different cell types