Phenotype MicroArray Technology is now available for applications with nearly all important species of bacteria and fungi. Simple protocols are available for testing nearly 2000 cellular phenotypes simultaneously.
Uses with microbial cells
Determine gene functions.
Compare gene knock-out mutants to wild types.
Compare naturally-isolated strains with different genetic backgrounds.
Identify novel antimicrobial targets
by finding genes unique to pathogenic
microorganisms.
Find phenotypes present in pathogenic
but not in non-pathogenic strains.
Find phenotypes present in pathogenic microbes but not in host cells (animal or plant).
Test antimicrobial targets and drug
leads by comparative phenotyping.
Determine MOA of drug leads.
Compare phenotypic changes caused
by target gene knockout versus drug
addition.
Bioprocess improvement
Compare and analyze different generations of production strains.
QC fingerprint production strains.
Scan 2000 culture conditions simultaneously to optimize the growth medium for product yield.
General cell characterization
Determine metabolic properties of any microbe.
Determine drug/chemical sensitivities.
Available for microbial cells
To view the tests in the PM sets, click on the map links below.
PM-1 to PM-10 Metabolic tests for bacteria and fungi.
