|Hayward, CA - December 18, 2006 - Biolog, Inc. announces the introduction of a new system capable of both microbial identification and kinetic characterization of cellular functions. Core laboratories in university settings and industry are often pursuing research projects such as strain characterization, detailed comparisons between pathogenic and non-pathogenic strains of bacteria, or product contamination studies where access to both technologies in a single analytical system will be extremely beneficial. The company's proprietary method for microbial identification allows laboratories to easily identify and characterize a wide range of gram-negative and gram-positive bacteria across diverse fields of microbiology. With the added capabilities of Phenotype MicroArray"! technology for elucidation and kinetic quantitation of phenotypes, researchers are able to measure cell pathway activities and phenotypes by analyzing cells under thousands of culture conditions. This provides data and insight essential to understanding variations among bacterial strains, correlating genotypes to phenotypes, discovering new targets for antimicrobial compounds, improving and optimizing bioprocesses, and more.
Biolog microbial identification is based on the use of 95 different carbon compounds contained in a convenient pre-filled microtiter format to measure metabolic reactions. This diverse set of tests enables the system to identify microorganisms other kit-based methods do not recognize or often misidentify. After inoculation and incubation, a characteristic metabolic pattern or "fingerprint" is generated by the organism and compared to hundreds of on-board profiles to interpret and confirm a species identification with a demonstrated level of accuracy that is comparable to molecular methods.
Phenotype MicroArrays provide a comprehensive overview of cellular pathways and phenotypes in a single experiment. Utilizing panels of up to 1920 phenotypic tests, researchers are able to evaluate cell changes under thousands of physiological states and culture conditions in a simple, rapid, efficient and cost-effective manner to expand their understanding of cellular physiology and species diversity.
The OmniLog Combo System includes an OmniLog Reader, multimedia computer, printer, LCD flat panel monitor, and bioinformatics software capable of handling both microbial identification and Phenotype MicroArray assays. Consumables, organism databases and other accessories are purchased separately depending on user needs.
Biolog, a privately held company based in Hayward, CA, is focused in cell-based assays with a continuing 22 year history of developing important and innovative technology and products. Biolog is a pioneer in the development of powerful cell analysis tools for solving critical problems in clinical, pharmaceutical, and biotechnology research and development. The company's unique Phenotype MicroArray technology and OmniLog PM Systems can be used in assays of cells of all types, from microbial to mammalian. Applications are very broad in scope - including basic research into the understanding of cell biology, cell metabolism fingerprinting, bioprocess optimization, and discovery and development of new drugs and other bioactive agents. Further information can be obtained at the company's website, www.biolog.com.